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Note 1 - Summary of Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2019
Notes Tables  
Disaggregation of Revenue [Table Text Block]
   
Three Months Ended
 
   
March 31,
 
Source
 
2019
   
2018
 
Royalty income
  $
4,161
    $
3,058
 
Other revenue
   
120
     
131
 
Total revenue
 
$
4,281
   
$
3,189
 
Property, Plant and Equipment [Table Text Block]
   
March 31,
   
December 31,
 
   
2019
   
2018
 
Machinery and equipment
  $
3,887
    $
2,992
 
Leasehold improvements
   
3,034
     
1,734
 
Computer equipment
   
621
     
721
 
Furniture and fixtures
   
878
     
878
 
Construction in progress
   
455
     
317
 
Property and equipment, gross
   
8,875
     
6,642
 
Less - accumulated depreciation
   
(2,813
)    
(2,698
)
Property and equipment, net
 
$
6,062
   
$
3,944