Note 8 - Commitments and Contingencies (Tables)

12 Months Ended

Dec. 31, 2018

Notes Tables

Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]

Years ending	Minimum Annual
December 31,	Payments
2019	$	1,935
2020		1,969
2021		2,003
2022		2,134
2023		2,173
Thereafter		16,375
Total	$	26,589

Licensing Service and Supply Agreements [Table Text Block]

	Paid from inception/acquisition to December 31, 2018		Future Commitments (1)		Terms
Amgen Fremont, Inc. (formerly Abgenix)	$	1,350	$	5,750	Milestones and royalties to use XenoMouse ® technology for generating fully human antibodies to PSMA LLC’s PSMA antigen.
Former member of PSMA LLC	$	466	$	52,188	Annual minimum royalty payments and milestones to use technology related to PSMA.
Selexis Commercial License Agreement	$	125	$	1,799	Milestones and royalties to use Selexis technology related to PSMA Antibodies.
University of Zurich and the Paul Scherrer Institute	$	565	$	1,125	Annual maintenance and license fee payments, milestones and royalties in respect of licensed technology related to 1404.
University of Western Ontario 2003 Agreement	$	39	$	145	Annual minimum royalty, administration and milestone payments in respect of licensed technology related to AZEDRA.
Johns Hopkins University Technology	$	250	$	2,685	Annual minimum royalty payments and milestones to use technology related to PyL.