Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017
Cash flows from operating activities:
Net loss	$ (28,596)	$ (32,996)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	3,178	2,189
Depreciation and amortization	590	544
Gain on sale of fixed assets		10
Paid in-kind interest		(13)
Non-cash interest expense	137	122
Deferred income tax	(96)
Change in fair value of contingent consideration liability	2,100	2,600
Changes in assets and liabilities:
Accounts receivable	164	2,148
Other current assets	63	1,026
Other assets
Accounts payable	(2,797)	557
Accrued expenses	(77)	(1,718)
Other current liabilities
Other liabilities	145	162
Net cash used in operating activities	(25,189)	(25,369)
Cash flows from investing activities:
Purchases of property and equipment	(502)	(240)
Proceeds from sale of fixed assets		37
Net cash used in investing activities	(502)	(203)
Cash flows from financing activities:
Net proceeds from issuance of common stock in connection with at-the-market offering	24,815
Return of estimated interest payment for noncontrolling interest		153
Proceeds from exercise of stock options		411
Repayment of debt	(2,179)
Net cash provided by financing activities	22,636	564
Effect of currency rate changes on cash, cash equivalents and restricted cash	(93)	60
Net decrease in cash, cash equivalents, and restricted cash	(3,148)	(24,948)
Cash, cash equivalents, and restricted cash at beginning of period	92,164	140,910
Cash, cash equivalents, and restricted cash at end of period	89,016	115,962
Cash, cash equivalents, and restricted cash information
Cash, cash equivalents, and restricted cash at beginning of period	$ 92,164	$ 140,910