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Note 5 - Accounts Receivable (Tables)
6 Months Ended
Jun. 30, 2018
Notes Tables  
Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]
   
June 30,
   
December 31,
 
   
2018
   
2017
 
Royalties
  $
3,530
    $
3,683
 
Collaborators
   
4
     
13
 
Other
   
309
     
276
 
Accounts receivable, net
 
$
3,843
   
$
3,972