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Note 1 - Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2018
Notes Tables  
Disaggregation of Revenue [Table Text Block]
   
Three months ended
   
Six months ended
 
   
June 30, 2018
   
June 30, 2018
 
Royalty income
  $
3,530
    $
6,588
 
License revenue
   
333
     
463
 
Other revenue
   
15
     
16
 
Total revenue
 
$
3,878
   
$
7,067
 
Property, Plant and Equipment [Table Text Block]
   
June 30,
   
December 31,
 
   
2018
   
2017
 
Machinery and equipment
  $
2,993
    $
2,516
 
Leasehold improvements
   
1,734
     
1,734
 
Computer equipment
   
712
     
714
 
Furniture and fixtures
   
878
     
874
 
Construction in progress
   
20
     
-
 
Property and equipment, gross
   
6,337
     
5,838
 
Less - accumulated depreciation
   
(2,198
)    
(1,716
)
Property and equipment, net
 
$
4,139
   
$
4,122