Note 7 - Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands	Jun. 30, 2017	Dec. 31, 2016
Accrued consulting and clinical trial costs	$ 6,404	$ 6,933
Loss contingency for litigation	3,850	4,000
Accrued payroll and related costs	1,452	1,957
Accrued legal and professional fees	875	1,123
Other	1,525	1,777
Accrued expenses	$ 14,106	$ 15,790