Organization and Business (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	1 Months Ended	3 Months Ended	12 Months Ended
	Jul. 31, 2013	Mar. 31, 2014	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Organization and Business [Abstract]
Common stock, issued (in shares)	9,775	8,750		8,750	9,775
Common stock public offering price (in dollars per share)				$ 4.60	$ 4.40
Common stock public offering proceeds	$ 40,078	$ 37,459	$ 0	$ 37,459	$ 40,078
Funding and Financial Matters [Abstract]
Cash and cash equivalents at end of period			74,103	119,302	65,860	$ 58,838
Decrease in cash and cash equivalents			$ (45,199)	53,442	$ 7,022
Minimum number of years cash will fund operations			1 year
Proceeds from future sales of common stock under an agreement with investment bank				50,000
Milestone Revenue from Valeant				$ 40,000