Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Schedule of deferred tax assets and liabilities

Deferred tax assets and liabilities as of December 31, 2015 and 2014, consisted of the following:

	2015			2014
Deferred tax assets:
Depreciation and amortization	$	2,215		$	5,770
R&E tax credit carry-forwards		19,284			18,612
NYS investment tax credit carry-forwards		1,087			1,090
AMT credit carry-forwards		211			211
Net operating loss carry-forwards		226,639			205,792
Capitalized research and development expenditures		15,149			20,280
Stock compensation		12,250			13,848
Other items		2,562			-
Total gross deferred tax assets		279,397			265,603
Less: Valuation allowance		(279,397	)		(265,603	)
Deferred tax assets		-			-
Deferred tax liability		(11,199	)		(11,332	)
Net deferred tax liability	$	(11,199	)	$	(11,332	)

Schedule of reconciliation of income taxes

The following is a reconciliation of income taxes computed at the Federal statutory income tax rate to the actual effective income tax provision during 2015, 2014 and 2013:

	2015		2014		2013

U.S. Federal statutory rate		34.0%		34.0%		34.0%
State income taxes, net of Federal benefit		4.8		8.0		5.4
Foreign rate differential		(0.1)		-		-
Research and experimental tax credit		1.7		(16.0)		3.8
Effect of federal and state tax rate changes		(4.8)		1.6		(8.7)
Permanent differences		(1.4)		15.1		0.1
Stock option shortfalls		(6.1)		38.1		(3.8)
New York NOL adjustment		3.8		-		-
Change in valuation allowance		(31.6)		(109.6)		(30.0)
Income tax benefit		0.3%		(28.8)%		0.8%

Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]

The following is a tabular reconciliation of the total amounts of unrecognized tax benefits for the years ended December 31, 2015 and 2014.

	2015		2014

Beginning uncertain tax benefits	$	2,661	$	2,661
Current year - increases		-		-
Current year - decreases		-		-
Settlements		-		-
Expired statuses		-		-
Ending uncertain tax benefits	$	2,661	$	2,661