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Fair Value Measurements (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Dec. 31, 2014
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]          
Contingent consideration liability $ 18,300   $ 18,300   $ 17,200
Recurring [Member]          
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]          
Contingent consideration liability 18,300   18,300   17,200
Money Market Funds 92,829   92,829   112,808
Asset, total 92,829   92,829   112,808
Liability, total 18,300   18,300   17,200
Recurring [Member] | Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]          
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]          
Contingent consideration liability 0   0   0
Money Market Funds 92,829   92,829   112,808
Asset, total 92,829   92,829   112,808
Liability, total 0   0   0
Recurring [Member] | Significant Other Observable Inputs (Level 2) [Member]          
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]          
Contingent consideration liability 0   0   0
Money Market Funds 0   0   0
Asset, total 0   0   0
Liability, total 0   0   0
Recurring [Member] | Significant Unobservable Inputs (Level 3) [Member]          
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]          
Contingent consideration liability 18,300   18,300   17,200
Money Market Funds 0   0   0
Asset, total 0   0   0
Liability, total 18,300   $ 18,300   $ 17,200
Azedra commercialization [Member]          
Fair Value Measurements, Quantitative Information          
Period of milestone expected achievement     2018   2018
Fair Value 2,400   $ 2,400   $ 2,300
Valuation technique     Probability adjusted discounted cash flow model   Probability adjusted discounted cash flow model
Discount Rate     10.00%   10.00%
Probability of success     40.00%   40.00%
MIP - 1404 commercialization [Member]          
Fair Value Measurements, Quantitative Information          
Period of milestone expected achievement     2019   2019
Fair Value 4,000   $ 4,000   $ 3,800
Valuation technique     Probability adjusted discounted cash flow model   Probability adjusted discounted cash flow model
Discount Rate     10.00%   10.00%
Probability of success     59.00%   59.00%
MIP-1095 commercialization [Member]          
Fair Value Measurements, Quantitative Information          
Period of milestone expected achievement     2023   2023
Fair Value 500   $ 500   $ 400
Valuation technique     Probability adjusted discounted cash flow model   Probability adjusted discounted cash flow model
Discount Rate     10.00%   10.00%
Probability of success     19.00%   19.00%
Net sales targets [Member]          
Fair Value Measurements, Quantitative Information          
Fair Value 11,400   $ 11,400   $ 10,700
Valuation technique     Monte-Carlo simulation   Monte-Carlo simulation
Net sales targets [Member] | Minimum [Member]          
Fair Value Measurements, Quantitative Information          
Period of milestone expected achievement     2019   2019
Discount Rate     3.50%   3.50%
Probability of success     19.00%   19.00%
Net sales targets [Member] | Maximum [Member]          
Fair Value Measurements, Quantitative Information          
Period of milestone expected achievement     2026   2026
Discount Rate     12.00%   12.00%
Probability of success     59.00%   59.00%
Net sales targets [Member] | Weighted average [Member]          
Fair Value Measurements, Quantitative Information          
Probability of success     37.40%   37.40%
Contingent Consideration Liability [Member]          
Summary of activities in financial instruments with significant Level 3 inputs [Roll Forward]          
Balance at beginning of period 17,500 $ 16,200 $ 17,200 $ 15,700 $ 15,700
Total realized/unrealized gains (losses)          
Fair value change to contingent consideration included in net loss 800 400 1,100 900  
Balance at end of period 18,300 16,600 18,300 16,600 $ 17,200
Changes in unrealized gains or losses for the period included in earnings (or changes in net assets) for liabilities held at the end of the reporting period $ 800 $ 400 $ 1,100 $ 900