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Income Taxes (Details) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Income Taxes [Abstract]      
Income tax provision (benefit) $ (989,000)us-gaap_IncomeTaxExpenseBenefit $ (362,000)us-gaap_IncomeTaxExpenseBenefit $ 0us-gaap_IncomeTaxExpenseBenefit
Deferred tax assets and liabilities [Abstract]      
Depreciation and amortization 5,770,000us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment 6,165,000us-gaap_DeferredTaxAssetsPropertyPlantAndEquipment  
R&E tax credit carry-forwards 5,270,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch 5,025,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch  
NYS investment tax credit carry-forwards 1,090,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsForeign 1,095,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsForeign  
AMT credit carry-forwards 211,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsAlternativeMinimumTax 211,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsAlternativeMinimumTax  
Net operating loss carry-forwards 204,974,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards 190,263,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards  
Capitalized research and development expenditures 20,280,000pgnx_DeferredTaxAssetsCapitalizedResearchAndDevelopmentExpenditures 25,231,000pgnx_DeferredTaxAssetsCapitalizedResearchAndDevelopmentExpenditures  
Stock compensation 13,848,000us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits 13,826,000us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits  
Other items 0us-gaap_DeferredTaxAssetsOther 1,097,000us-gaap_DeferredTaxAssetsOther  
Total gross deferred tax assets 251,443,000us-gaap_DeferredTaxAssetsGross 242,913,000us-gaap_DeferredTaxAssetsGross  
Less: Valuation allowance (251,443,000)us-gaap_DeferredTaxAssetsValuationAllowance (242,913,000)us-gaap_DeferredTaxAssetsValuationAllowance  
Deferred tax assets: 0us-gaap_DeferredTaxAssetsNet 0us-gaap_DeferredTaxAssetsNet  
Deferred tax liability - long term (11,332,000)us-gaap_DeferredTaxLiabilities (12,321,000)us-gaap_DeferredTaxLiabilities  
Net deferred tax liability (11,332,000)us-gaap_DeferredTaxAssetsLiabilitiesNet (12,321,000)us-gaap_DeferredTaxAssetsLiabilitiesNet  
Reconciliation of income taxes computed at the Federal statutory income tax rate to the actual effective income tax [Abstract]      
U.S. Federal statutory rate 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate (34.00%)us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate (35.00%)us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
State income taxes, net of Federal benefit 13.20%us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes (4.90%)us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes (5.40%)us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
Research and experimental tax credit (15.80%)us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch (3.80%)us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch 0.00%us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
Effect of federal and state tax rate changes 1.50%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate 8.70%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate 0.00%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
Permanent differences 47.90%us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther 3.20%us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther 4.20%us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
Change in valuation allowance (109.60%)us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance 30.00%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance 36.20%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
Income tax provision (benefit) (28.80%)us-gaap_EffectiveIncomeTaxRateContinuingOperations (0.80%)us-gaap_EffectiveIncomeTaxRateContinuingOperations 0.00%us-gaap_EffectiveIncomeTaxRateContinuingOperations
Net operating loss carryforwards - federal 557,200,000pgnx_OperatingLossCarryforwardsFederal    
Net operating loss carryforwards - state 475,600,000pgnx_OperatingLossCarryforwardsState    
Net operating loss carry-forwards not reflected in deferred tax assets 18,200,000pgnx_OperatingLossCarryforwardsNotReflectedInDeferredTaxAssets    
Valuation allowance related to net operating loss carryforwards attributable to excess tax deductions for equity compensation 11,200,000us-gaap_OperatingLossCarryforwardsValuationAllowance    
Unrecognized tax benefits (989,000)us-gaap_UnrecognizedTaxBenefits (362,000)us-gaap_UnrecognizedTaxBenefits 0us-gaap_UnrecognizedTaxBenefits
Deferred tax liability - long term 11,332,000us-gaap_DeferredTaxLiabilities 12,321,000us-gaap_DeferredTaxLiabilities  
Tax Credit Carryforward, Amount 5,300,000us-gaap_TaxCreditCarryforwardAmount    
Income Taxes [Abstract]      
Unrecognized tax benefits 2,661,000pgnx_UncertainTaxBenefits 2,661,000pgnx_UncertainTaxBenefits 2,661,000pgnx_UncertainTaxBenefits
Current year - increases 0us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions 0us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions  
Current year - decreases 0us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromCurrentPeriodTaxPositions 0us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromCurrentPeriodTaxPositions  
Settlements 0us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromSettlementsWithTaxingAuthorities 0us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromSettlementsWithTaxingAuthorities  
Expired statuses $ 0us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations $ 0us-gaap_UnrecognizedTaxBenefitsReductionsResultingFromLapseOfApplicableStatuteOfLimitations