STATEMENTS OF OPERATIONS (Unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2012	Mar. 31, 2011
Revenues:
Royalty income	$ 1,834	$ 0
Collaboration revenue	291	1,083
Research grants	86	1,264
Other revenues	15	41
Total revenues	2,226	2,388
Expenses:
Research and development	10,909	19,179
License fees - research and development	40	364
Royalty expense	185	57
General and administrative	3,721	5,197
Depreciation and amortization	472	536
Total expenses	15,327	25,333
Operating loss	(13,101)	(22,945)
Other income:
Interest income	15	18
Total other income	15	18
Net loss	$ (13,086)	$ (22,927)
Net loss per share - basic and diluted	$ (0.39)	$ (0.69)
Weighted-average shares - basic and diluted	33,761	33,273