Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (Nos. 333-52277, 333-120508, 333-124910,  333-143670, 333-160389, 333-160392, 333-168124) of Progenics Pharmaceuticals, Inc. of our report dated March 11, 2011 relating to the financial statements, and the effectiveness of internal control over financial reporting, which appears in this Form 10-K.

/s/ PricewaterhouseCoopers LLP

New York, New York

March 11,  2011