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Note 5 - Share-based Compensation (Tables)
3 Months Ended
Mar. 31, 2018
Notes Tables  
Share-based Compensation, Stock Options, Activity [Table Text Block]
   
Three Month Period Ended
 
   
March 31,
2018
 
   
 
 
 
 
Wtd. Avg.
 
   
 
 
 
 
Exercise
 
   
Options
   
Price
 
Outstanding at beginning of year
   
2,390,012
    $
1.85
 
Granted
   
    $
N/A
 
Exercised
   
(62,438
)
  $
1.16
 
Forfeited
   
(730
)
  $
2.62
 
Expired
   
    $
N/A
 
Outstanding at March 31, 2018
   
2,326,844
    $
1.87
 
                 
Stock options exercisable at March 31, 2018
   
1,637,951
    $
1.76
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
   
Three Month Period Ended
 
   
March 31,
 
   
201
8
   
201
7
 
Risk free interest rate
   
N/A
     
2.07
%
Dividend yield
   
N/A
     
0.0
%
Expected term (in years)
   
N/A
     
5.18
 
Volatility
   
N/A
     
75
%
Schedule of Share-based Compensation, Restricted Stock and Restricted Stock Units Activity [Table Text Block]
   
Three Month Period Ended
 
   
March 31,
2018
 
   
Number of
Restricted
Shares
   
Grant-Date
Fair Value
 
Unvested outstanding at beginning of year
   
237,926
    $
1.79
 
Granted
   
161,768
    $
6.00
 
Vested
   
(55,613
)
  $
1.78
 
Forfeited
   
(6,100
)
  $
1.76
 
Unvested outstanding at March 31, 2018
   
337,981
    $
3.80
 
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]
   
Three Month Period Ended
 
   
March 31,
 
   
2018
   
2017
 
Research and development costs
  $
65,595
    $
59,265
 
Sales and marketing costs
   
68,513
     
59,619
 
General and administrative costs
   
190,949
     
168,198
 
Cost of product sales
   
48,368
     
42,813
 
Total
  $
373,425
    $
329,895