10. Share-based Compensation (Tables)

9 Months Ended

12 Months Ended

Sep. 30, 2013

Dec. 31, 2012

Notes to Financial Statements

Weighted average assumptions of share based payment

	Three Month Period Ended				Nine Month Period Ended
	September 30,				September 30,
	2013		2012		2013		2012
Risk free interest rate		2.25%		0.71%		2.25%		0.78%
Dividend yield		0.0%		0.0%		0.0%		0.0%
Expected term (in years)		7		7		7		6.6
Volatility		105.20%		101.57%		105.20%		102.76%

Stock compensation expense

	Three Month Period Ended				Nine Month Period Ended
	September 30,				September 30,
	2013		2012		2013		2012
Research and development costs	$	5,893	$	6,954	$	19,801	$	20,441
Sales and marketing costs		1,265		630		2,525		840
General and administrative costs		71,294		42,720		120,608		118,542
Cost of product sales		9,782		6,830		32,853		14,924
Total	$	88,234	$	57,134	$	175,787	$	154,747

Summary of stock option activity

	Nine Month Period Ended
	September 30, 2013
				Wtd. Avg.
				Exercise
	Shares			Price
Outstanding at beginning of year		20,329,602		$	0.09
Granted		175,000			0.75
Exercised		(355,855	)		0.07
Unvested Shares Forfeited		(380,000	)		0.12
Expired		(25,000	)		0.08
Outstanding at September 30, 2013		19,743,747		$	0.09
Stock options exercisable at September 30, 2013		16,261,588		$	0.08

	Year Ended						Year Ended
	December 31, 2012						December 31, 2011
				Wtd. Avg.						Wtd. Avg.
				Exercise						Exercise
	Shares			Price			Shares			Price
Outstanding at beginning of year		17,873,227		$	0.08			14,564,815		$	0.09
Granted		3,150,000			0.12			6,220,873			0.08
Exercised		-			-			-			-
Forfeited		(643,625	)		(0.12	)		(2,912,461	)		(0.08	)
Outstanding at end of year		20,379,602		$	0.09			17,873,227		$	0.08
Stock options exercisable at year end		14,105,066		$	0.08			9,667,990		$	0.08