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Stock-Based Compensation (Details 3) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]    
Total Share Based Compensation $ 1,270,203 $ 776,994
Research and development costs    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]    
Total Share Based Compensation 236,972 151,849
Sales and marketing costs    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]    
Total Share Based Compensation 230,461 176,878
General and administrative costs    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]    
Total Share Based Compensation 638,346 426,035
Cost of product sales    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]    
Total Share Based Compensation 164,424 2,794
Joint Venture Restructuring Charges    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]    
Total Share Based Compensation $ 0 $ 19,438