-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 It6/CKDL4uSQVn7SaOaexCFwkYydrHn4wtSwUAXEuNceOUPAPnyRaeAJLoO6Jk7z
 30BX3FOV4bDOtw8x22jOFA==

<SEC-DOCUMENT>0001341150-07-000003.txt : 20070629
<SEC-HEADER>0001341150-07-000003.hdr.sgml : 20070629
<ACCEPTANCE-DATETIME>20070629202347
ACCESSION NUMBER:		0001341150-07-000003
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070629
FILED AS OF DATE:		20070629
DATE AS OF CHANGE:		20070629

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOSITE INC
		CENTRAL INDEX KEY:			0000834306
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				330288606
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		11030 ROSELLE ST
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		6194554808

	MAIL ADDRESS:	
		STREET 1:		11030 ROSELLE ST
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BIOSITE DIAGNOSTICS INC
		DATE OF NAME CHANGE:	19960710

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Anacone Robert
		CENTRAL INDEX KEY:			0001341150

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-21873
		FILM NUMBER:		07952697

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		858-805-2724

	MAIL ADDRESS:	
		STREET 1:		9975 SUMMERS RIDGE ROAD
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgardoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-06-29</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0000834306</issuerCik>
        <issuerName>BIOSITE INC</issuerName>
        <issuerTradingSymbol>BSTE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001341150</rptOwnerCik>
            <rptOwnerName>Anacone Robert</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>897 COFAIR COURT</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>SOLANA BEACH</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92075</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle>Senior Vice President    World</officerTitle>
            <otherText>Senior Vice President    World</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Non-Qualified Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>55.23</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-06-29</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>D</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>31250</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-10-31</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>31250</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This option, which provided for vesting in sixteen equal quarterly installments over a four-year period commencing on the date of grant, was assumed by Inverness Medical Innovations (&quot;Inverness&quot;) pursuant to a merger agreement between the Issuer and Inverness and replaced with an option to purchase 55,987 shares of Inverness common stock for $30.83 per share.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>By: Robyn Shutak  For: Robert B. Anacone</signatureName>
        <signatureDate>2007-06-29</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----