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Note 8 - Income Taxes - Reconciliation of Income Tax Benefit (Details)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
U.S. federal statutory rate applied to pretax loss 21.00% 21.00%
State income tax (benefit) 3.90% 3.90%
Permanent differences (0.00%) (0.00%)
NOL carryforward expiration (4.30%) (15.60%)
R&D tax credits, net of expiration 6.40% 4.60%
Change in valuation allowance and other adjustments (27.00%) (13.90%)
Effective tax rate 0.00% 0.00%