Note 8 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2023

Notes Tables

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	2023			2022
Deferred tax assets:
Net operating loss carryforward	$	25,527,210		$	19,764,569
Research and development tax credit carryforward		3,870,460			2,202,603
Stock-based compensation expense		552,886			330,553
Accrued expenses		29,728			663,211
Total deferred tax assets		29,980,284			22,960,936
Deferred tax liabilities
Depreciation		45,122			51,466
Net deferred tax assets		29,935,162			22,909,470
Valuation allowance		(29,935,162	)		(22,909,470	)
Net deferred tax asset after reduction for valuation allowance	$	-0-		$	-0-

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	2023			2022
U.S. federal statutory rate applied to pretax loss		21.0	%		21.0	%
State income tax (benefit)		3.9			3.9
Permanent differences		(0.0	)		(0.0	)
NOL carryforward expiration		(4.3	)		(15.6	)
R&D tax credits, net of expiration		6.4			4.6
Change in valuation allowance and other adjustments		(27.0	)		(13.9	)
Effective tax rate		0.0	%		0.0	%