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Note 6 - Stock-based Compensation Expense (Tables)
12 Months Ended
Dec. 31, 2023
Notes Tables  
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

Weighted average risk-free interest rates

    3.54 %

Expected dividend yield

    0.0 %

Expected life of option (in years)

    7.0  

Expected volatility

    160.0 %
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
   

2023

   

2022

 

Stock options:

               

Research and development

  $ 291,094     $ 225,031  

General and administrative

    564,030       548,346  

Total stock option expense

    855,124       773,377  

Stock awards (consultants):

               

General and administrative

    219,833       128,697  

Total stock-based compensation expense

  $ 1,074,957     $ 902,074