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Note 5 - Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2022
Notes Tables  
Schedule of Common Stock Reserved for Future Issuance [Table Text Block]
   

Shares

 

Stock warrants outstanding

    13,384,115  

Stock options outstanding

    2,058,800  

Stock options authorized for future grants

    16,700  

Total

    15,459,615  
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
   

Number

of Shares

   

Weighted-

Average

Exercise

Price

   

Weighted-

Average

Remaining

Contractual

Term (yrs)

   

Aggregate

Intrinsic

Value

 

Outstanding at December 31, 2021

    962,300     $ 3.18       9.3     $ 499,660  

Granted

    1,096,500       0.76                  

Exercised

    -       -                  

Forfeited or expired

    -       -                  

Outstanding at December 31, 2022

    2,058,800     $ 1.89       9.2     $ -  

Exercisable at December 31, 2022

    588,089     $ 3.12       8.3     $ -  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

Issue Date

 

Number

of Shares

   

Exercise

Price

 

Expiration

June 2020

    120,000     $ 1.65  

June 2025

September 2020

    2,396,631       5.00  

September 2025

September 2020

    128,000       5.50  

March 2024

February 2021

    72,000       6.88  

August 2024

September 2021

    100,000       13.00  

September 2026

January 2022

    3,067,484       3.26  

February 2027

May 2022

    7,500,000       1.65  

May 2028

Outstanding at December 31, 2022

    13,384,115