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Note 3 - Balance Sheet Components (Tables)
3 Months Ended
Mar. 31, 2023
Notes Tables  
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
   

March 31,

2023

   

December 31,

2022

 

Prepaid clinical trial costs (current portion)

  $ 1,962,913     $ 1,171,077  

Prepaid insurance premiums

    72,013       107,876  

Prepaid rent

    13,045       13,045  

Other prepaid expenses

    91,000       34,000  

Total prepaid expenses

  $ 2,138,971     $ 1,325,998  
Property, Plant and Equipment [Table Text Block]
   

March 31,

2023

   

December 31,

2022

 

Equipment and furnishings

  $ 725,812     $ 725,812  

Leasehold improvements

    115,605       115,605  

Total property and equipment

    841,417       841,417  

Accumulated depreciation and amortization

    (623,824 )     (606,505 )

Total property and equipment, net

  $ 217,593     $ 234,912  
Schedule of Other Assets [Table Text Block]
   

March 31,

2023

   

December 31,

2022

 

Prepaid clinical trial costs (noncurrent portion)

  $ 1,106,778     $ 2,083,276  

Prepaid technology license fees

    80,000       80,000  

Deposits

    11,010       11,010  

Total other assets

  $ 1,197,788     $ 2,174,286  
Schedule of Accrued Liabilities [Table Text Block]
   

March 31,

2023

   

December 31,

2022

 

Accrued technology license fees

  $ 2,000,000     $ 2,000,000  

Payroll-related liabilities

    127,553       550,810  

Other accrued expenses

    1,123,507       449,402  

Total accrued expenses

  $ 3,251,060     $ 3,000,212