Note 4 - Commitments (Details Textual) - Office and Laboratory Lease Agreement [Member]	12 Months Ended
Dec. 31, 2022 USD ($) ft²	Dec. 31, 2021 USD ($)
Area of Real Estate Property \| ft²	8,400
Operating Lease, Expense	$ 176,797	$ 166,242
Lessee, Operating Lease, Liability, to be Paid, Year One	182,000
Lessee, Operating Lease, Liability, to be Paid, Year Two	187,000
Lessee, Operating Lease, Liability, to be Paid, Year Three	$ 193,000

Area of a real estate property.

No definition available.

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- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 6
-URI https://asc.fasb.org/extlink&oid=128292326&loc=SL77918701-209980

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in third fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

+ References

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in second fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

+ References

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of operating lease expense. Excludes sublease income.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 45
-Paragraph 4
-Subparagraph (b)
-URI https://asc.fasb.org/extlink&oid=123391704&loc=SL77918638-209977

+ Details

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Balance Type:	debit
Period Type:	duration

- Details

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Balance Type:
Period Type: