Note 9 - Income Taxes - Reconciliation of Income Tax Benefit (Details) - USD ($)	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020
U.S. federal statutory rate applied to pretax loss	$ (3,899,767)	$ (621,194)
Permanent differences		65
Research and development credits	(377,183)	(66,574)
Change in valuation allowance, net of expired items and other adjustments	4,276,950	687,703
Reported income tax expense	$ 0	$ 0

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets.

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The amount of income tax expense or benefit for the period computed by applying the domestic federal statutory tax rates to pretax income from continuing operations.

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