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Note 3 - Property and Equipment - Schedule of Property and Equipment (Details) - USD ($)
Sep. 30, 2021
Dec. 31, 2020
Dec. 31, 2019
Property and equipment, gross $ 707,159 $ 659,441 $ 661,918
Accumulated depreciation and amortization (538,506) (511,700) (651,312)
Property and equipment, net 168,653 147,741 10,606
Laboratory Equipment [Member]      
Property and equipment, gross   532,100 534,577
Leasehold Improvements [Member]      
Property and equipment, gross $ 115,605 115,605 115,605
Other Furniture Fixtures And Equipment [Member]      
Property and equipment, gross   $ 11,736 $ 11,736