Note 3 - Property and Equipment - Schedule of Property and Equipment (Details) - USD ($)	Mar. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Property and equipment, gross	$ 661,918	$ 661,918	$ 674,596
Accumulated depreciation and amortization	(652,306)	(651,312)	(663,246)
Property and equipment, net	9,612	10,606	11,350
Laboratory Equipment [Member]
Property and equipment, gross	534,577	534,577	530,306
Leasehold Improvements [Member]
Property and equipment, gross	115,605	115,605	115,605
Other Furniture Fixtures And Equipment [Member]
Property and equipment, gross	$ 11,736	$ 11,736	$ 28,685

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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