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Note 10 - Common Stock and Stock-based Compensation (Details Textual)
3 Months Ended 9 Months Ended
Apr. 30, 2019
Sep. 30, 2019
USD ($)
$ / shares
shares
Sep. 30, 2018
USD ($)
Sep. 30, 2019
USD ($)
$ / shares
shares
Sep. 30, 2018
USD ($)
Stock Issued During Period, Shares, Issued for Services       41,954  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number, Ending Balance   28,800   28,800  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price, Ending Balance | $ / shares   $ 53.99   $ 53.99  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number   13,585   13,585  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price | $ / shares   $ 93.92   $ 93.92  
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total | $   $ 130,719   $ 130,719  
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition       1 year 219 days  
Stock Issued During Period, Value Expensed During the Period, Issued for Services | $   6,000 $ 57,143 $ 211,080 $ 142,856
Share-based Payment Arrangement, Option [Member]          
Share-based Payment Arrangement, Expense | $   $ 26,348 $ 85,370 $ 79,664 $ 132,569
Common Stock Purchase Warrants [Member]          
Class Of Warrant Or Right Issued During Period       100,002  
Class of Warrant or Right, Outstanding   294,302   294,302  
Class Of Warrant Or Right Outstanding Weighted Average Exercise Price | $ / shares   $ 7.50   $ 7.50  
Class Of Warrant Or Right Exercisable Number   227,634   227,634  
Class Of Warrant Or Right Exercisable Weighted Average Exercise Price | $ / shares   $ 7.50   $ 7.50  
Conversion from Series C, F and H Convertible Preferred Stock to Common Stock [Member]          
Conversion of Stock, Shares Issued       95,147,421  
Reverse Stock Split [Member]          
Stockholders' Equity Note, Stock Split, Conversion Ratio 500