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Note 12 - Subsequent Events	3 Months Ended
Note 12 - Subsequent Events	Mar. 31, 2019
Notes to Financial Statements
Subsequent Events [Text Block]	12. Subsequent Events Preferred Stock Transactions On April 26, 2019, we received $250,000 from the sale of 250 shares of our Series G Preferred Stock (see Note 9 ) and we issued additional Series I Warrants to purchase 33,334 shares of our common stock. During May 2019, holders of our preferred stock converted 94 shares of our Series F Preferred Stock into 53,600 shares of our common stock. Reverse Stock Split On April 30, 2019, we effected a one -for- five hundred reverse split of our common stock by the filing of an amendment to our certificate of incorporation with the State of Delaware. All share and per share information in our condensed consolidated financial statements and notes that relate to our common stock has been retroactively restated to reflect the reverse stock split.