Note 10 - Grants and Collaboration Revenue (Details Textual) - USD ($)	3 Months Ended	6 Months Ended
Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Revenue from Grants	$ 352,137	$ 166,280	$ 647,872	$ 213,880
Revenue from Collaboration	95,000		95,000
NIH Grants [Member]
Revenue from Grants	257,137	$ 166,280	552,872	$ 213,880
Unused Grant Funds	$ 910,774		$ 910,774

Revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1(e))
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

Name:	us-gaap_RevenueFromGrants
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration