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Consolidated Statements of Operations - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Grant revenues $ 295,735 $ 47,600 $ 828,918 $ 428,081 $ 882,956
Operating expenses:          
Research and development 551,795 438,004 1,970,859 1,693,102 1,812,969
General and administrative 292,667 906,505 2,131,426 1,429,731 1,807,605
Total operating expenses 844,462 1,344,509 4,102,285 3,122,833 3,620,574
Loss from operations (548,727) (1,296,909) (3,273,367) (2,694,752) (2,737,618)
Other income:          
Interest income 386 630 1,666 5,465 4,063
Total other income 386 630 1,666 5,465 4,063
Net loss $ (548,341) $ (1,296,279) $ (3,271,701) $ (2,689,287) $ (2,733,555)
Basic and diluted:          
Loss per common share (in dollars per share) $ (0.01) $ (0.04) $ (0.08) $ (0.08) $ (0.10)
Weighted average shares outstanding (in shares) 55,350,974 34,599,625 41,516,514 31,950,813 26,645,140