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Note 3 - Property and Equipment (Tables)
3 Months Ended 12 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Notes Tables    
Property, Plant and Equipment [Table Text Block]
   
March 31,
2017
   
December 31,
2016
 
Laboratory equipment
  $
530,306
    $
525,956
 
Leasehold improvements
   
115,605
     
115,605
 
Other furniture, fixtures & equipment
   
28,685
     
28,685
 
Total property and equipment
   
674,596
     
670,246
 
Accumulated depreciation and amortization
   
(622,316
)    
(615,418
)
Property and equipment, net
  $
52,280
    $
54,828
 
   
2016
   
2015
 
Laboratory equipment
  $
525,956
    $
525,956
 
Leasehold improvements
   
115,605
     
115,605
 
Other furniture, fixtures & equipment
   
28,685
     
28,685
 
Total property and equipment
   
670,246
     
670,246
 
Accumulated depreciation and amortization
   
(615,418
)    
(586,638
)
Property and equipment, net
  $
54,828
    $
83,608