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Note 5 - Property and Equipment Components (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Laboratory Equipment [Member]    
Property and equipment, gross $ 525,956 $ 525,956
Leasehold Improvements [Member]    
Property and equipment, gross 115,605 115,605
Other Furniture Fixtures And Equipment [Member]    
Property and equipment, gross 28,685 28,685
Property and equipment, gross 670,246 670,246
Accumulated depreciation and amortization (593,833) (586,638)
Property and equipment, net $ 76,413 $ 83,608