Financial Commitments and Contingencies and Key License Agreements - Components of Lease Expense (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2022	Mar. 31, 2021
Commitments and Contingencies Disclosure [Abstract]
Operating lease cost	$ 421	$ 466
Variable lease cost	99	125
Short-term lease cost	25	17
Total lease cost	$ 545	$ 608

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Amount of lease cost recognized by lessee for lease contract.

+ References

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Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.

+ References

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Amount of short-term lease cost, excluding expense for lease with term of one month or less.

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Amount of variable lease cost, excluded from lease liability, recognized when obligation for payment is incurred for finance and operating leases.

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