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Balance Sheet Account Detail - Summary of Cash and Cash Equivalents and Marketable Securities (Details) - USD ($)
$ in Thousands, shares in Millions
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Schedule of Investments [Line Items]      
Equity securities, FV-NI, cost $ 3,508   $ 3,512
Cash, cash equivalents, and short-term investments, amortized cost 87,587   97,269
Equity securities 4,655   5,718
Cash, cash equivalents, and short-term investments 89,214   100,647
Realized gain on sale of equity holdings 645 $ 2,856  
CASI Common Stock      
Schedule of Investments [Line Items]      
Equity securities $ 3,800    
Number of shares held in investment (in shares) 4.7    
Number of common shares sale in investments (in shares) 0.4    
Realized gain on sale of equity holdings $ 300    
Unicycive Therapeutics, Inc.      
Schedule of Investments [Line Items]      
Equity securities $ 900    
Number of shares held in investment (in shares) 0.7    
Number of common shares sale in investments (in shares) 0.2    
Realized gain on sale of equity holdings $ 200    
Cash and Cash Equivalents      
Schedule of Investments [Line Items]      
Equity securities 0   0
Cash, cash equivalents, and short-term investments 78,679   88,539
Marketable  Securities      
Schedule of Investments [Line Items]      
Equity securities 4,655   5,718
Cash, cash equivalents, and short-term investments 10,535   12,108
Money market funds      
Schedule of Investments [Line Items]      
Historical or Amortized Cost 56,326   66,322
Available-for-sale 56,326   66,322
Money market funds | Cash and Cash Equivalents      
Schedule of Investments [Line Items]      
Available-for-sale 56,326   66,322
Money market funds | Marketable  Securities      
Schedule of Investments [Line Items]      
Available-for-sale 0   0
Mutual funds      
Schedule of Investments [Line Items]      
Historical or Amortized Cost 5,400   5,218
Available-for-sale 5,880   6,390
Mutual funds | Cash and Cash Equivalents      
Schedule of Investments [Line Items]      
Available-for-sale 0   0
Mutual funds | Marketable  Securities      
Schedule of Investments [Line Items]      
Available-for-sale 5,880   6,390
Bank deposits      
Schedule of Investments [Line Items]      
Historical or Amortized Cost 22,353   22,217
Available-for-sale 22,353   22,217
Bank deposits | Cash and Cash Equivalents      
Schedule of Investments [Line Items]      
Available-for-sale 22,353   22,217
Bank deposits | Marketable  Securities      
Schedule of Investments [Line Items]      
Available-for-sale $ 0   $ 0