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Balance Sheet Account Detail
3 Months Ended
Mar. 31, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Balance Sheet Account Detail Balance Sheet Account Detail
The composition of selected financial statement captions that comprise the accompanying Condensed Consolidated Balance Sheets are summarized below:
(a) Cash and Cash Equivalents and Marketable Securities

We maintain cash balances with select major financial institutions. The Federal Deposit Insurance Corporation (FDIC) and other third parties insure a fraction of these deposits. Accordingly, these cash deposits are not insured against the possibility
of a substantial or complete loss of principal and are inherently subject to the credit risk of the corresponding financial institution.
Our investment policy requires that purchased investments may only be in highly-rated and liquid financial instruments and limits our holdings of any single issuer (excluding any debt or equity securities that may be received from our strategic partners in connection with an out-license arrangement).
The carrying amount of our equity securities, money market funds, and bank CDs approximates their fair value (utilizing “Level 1” or “Level 2” inputs) because of our ability to immediately convert these instruments into cash with minimal expected change in value. There were no material unrealized losses on our investment securities at March 31, 2022 or December 31, 2021.
The following is a summary of our presented composition of “cash and cash equivalents” and “marketable securities”:
Historical or Amortized CostFair
Value
Cash and Cash
Equivalents
Marketable
 Securities
March 31, 2022
Money market funds$56,326 $56,326 $56,326 $— 
Equity securities(1)
3,508 4,655 — 4,655 
Mutual funds5,400 5,880 — 5,880 
Bank deposits22,353 22,353 22,353 — 
Total cash and cash equivalents and marketable securities$87,587 $89,214 $78,679 $10,535 
December 31, 2021
Equity securities(1)
$3,512 $5,718 $— $5,718 
Money market funds66,322 66,322 66,322 — 
Bank deposits22,217 22,217 22,217 — 
Mutual funds5,218 6,390 — 6,390 
Total cash and cash equivalents and marketable securities$97,269 $100,647 $88,539 $12,108 
(1)Our aggregate equity holdings consist of 4.7 million common shares of CASI Pharmaceuticals, Inc., a NASDAQ-listed biopharmaceutical company, with a fair market value of $3.8 million as of March 31, 2022. We completed the sale of 0.4 million shares of common stock and recognized a $0.3 million gain within “other expense, net” within the accompanying Condensed Consolidated Statements of Operations for the three months ended March 31, 2022. Additionally, we hold 0.7 million common shares of Unicycive Therapeutics, Inc., a NASDAQ-listed biopharmaceutical company, with a fair market value of $0.9 million as of March 31, 2022. We completed the sale of 0.2 million shares of common stock and recognized a $0.2 million gain within “other expense, net” within the accompanying Condensed Consolidated Statements of Operations for the three months ended March 31, 2022.
(b)  Accounts Payable and Other Accrued Liabilities
“Accounts payable and other accrued liabilities” consists of the following:
March 31, 2022December 31, 2021
Trade accounts payable and other $25,305 $33,408 
Lease liability - current portion1,001 1,282 
Commercial Product Portfolio accruals (Note 7)6,269 6,568 
Accounts payable and other accrued liabilities $32,575 $41,258 
Amounts presented within “accounts payable and other accrued liabilities” in the accompanying Condensed Consolidated Balance Sheets for our categories of gross-to-net (“GTN”) estimates related to the Commercial Product Portfolio accruals were as follows:
Commercial/Medicaid Rebates and Government ChargebacksDistribution, Data, Inventory and
GPO Administrative Fees
Product Return AllowancesTotal
Balance as of December 31, 2020$2,601 $942 $4,299 $7,842 
(Less): Payments and credits against GTN accruals (1,159)— (115)(1,274)
Balance as of December 31, 2021$1,442 $942 $4,184 6,568 
(Less): Payments and credits against GTN accruals (35)— (264)(299)
Balance as of March 31, 2022$1,407 $942 $3,920 $6,269