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Summary of Significant Accounting Policies and Use of Estimates - Additional Information (Detail)
 3 Months Ended
Mar. 31, 2017
Accounting Policies [Line Items]  
Number of months customers are allowed to return products 6 months
Cash and equivalents maturities period 3 months
EVOMELA [Member]  
Accounting Policies [Line Items]  
Number of months customers are allowed to return products 12 months