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Gross-to-Net Product Sales and Significant Customers - Reconciliation of Gross-to-Net Product Sales (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Revenue, Net [Abstract]      
Gross product sales $ 244,770 $ 215,136 $ 284,685
Commercial rebates and government chargebacks (98,317) (61,283) (76,636)
Data and distribution fees, GPO fees, and inventory management fees (14,979) (15,613) (21,330)
Prompt pay discounts (755) (16) (260)
Product returns allowances (2,123) (1,373) 78
Net product sales $ 128,596 $ 136,851 $ 186,537