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Balance Sheet Account Detail - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Property, Plant and Equipment [Line Items]      
Depreciation expense $ 500 $ 700 $ 1,100
Intangible assets, net 164,234 190,335  
Intangible asset amortization expense 25,900 38,300 $ 24,300
MARQIBO IPR&D (NHL and further ALL indications) [Member]      
Property, Plant and Equipment [Line Items]      
Intangible assets, net $ 17,600 $ 17,600