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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Jh81olHowMaRrsVbpX7PdZwItImyxhp3DBG/1m/Lh9P8gwbWjoLvq1BG4vwrO1g4
 tiNHtWem5wLb595MtFrhvw==

<SEC-DOCUMENT>0001181431-08-049634.txt : 20080821
<SEC-HEADER>0001181431-08-049634.hdr.sgml : 20080821
<ACCEPTANCE-DATETIME>20080821172313
ACCESSION NUMBER:		0001181431-08-049634
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080819
FILED AS OF DATE:		20080821
DATE AS OF CHANGE:		20080821

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALPHA INNOTECH CORP
		CENTRAL INDEX KEY:			0000830736
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				581729436
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2401 MERCED ST.
		CITY:			SAN LEANDRO
		STATE:			CA
		ZIP:			94577
		BUSINESS PHONE:		5104839620

	MAIL ADDRESS:	
		STREET 1:		2401 MERCED ST.
		CITY:			SAN LEANDRO
		STATE:			CA
		ZIP:			94577

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	XTRANA INC
		DATE OF NAME CHANGE:	20010702

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BIOPOOL INTERNATIONAL INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTRX BIOPOOL LTD
		DATE OF NAME CHANGE:	19890716

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Henighan Michael P
		CENTRAL INDEX KEY:			0001443614

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14257
		FILM NUMBER:		081032863

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		510-904-5610

	MAIL ADDRESS:	
		STREET 1:		ALPHA INNOTECH CORPORATION
		STREET 2:		2401 MERCED STREET
		CITY:			SAN LEANDRO
		STATE:			CA
		ZIP:			94577
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd216664.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-08-19</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000830736</issuerCik>
        <issuerName>ALPHA INNOTECH CORP</issuerName>
        <issuerTradingSymbol>APNO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001443614</rptOwnerCik>
            <rptOwnerName>Henighan Michael P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ALPHA INNOTECH CORPORATION</rptOwnerStreet1>
            <rptOwnerStreet2>2401 MERCED STREET</rptOwnerStreet2>
            <rptOwnerCity>SAN LEANDRO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94577</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Financial Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right-to-buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.90</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-08-19</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>30000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-08-19</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>30000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>30000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">1/4th of the total number of shares subject to the option shall vest at the one year anniversary of the Vesting Commencement Date of August 19, 2008, and 1/48th of the total number of shares subject to the option shall vest on each monthly anniversary thereafter.</footnote>
        <footnote id="F2">Not applicable.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Henighan Michael P</signatureName>
        <signatureDate>2008-08-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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