UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

        Date of Report (Date of earliest event reported): MARCH 20, 2006

                              ALPHA INNOTECH CORP.
             (Exact name of registrant as specified in its charter)


          DELAWARE                     1-14257                   58-1729436
(State or other jurisdiction         (Commission               (IRS Employer
      of incorporation)              File Number)            Identification No.)


          2401 MERCED STREET, SAN LEANDRO, CALIFORNIA              94577
            (Address of principal executive offices)             (Zip Code)

       Registrant's telephone number, including area code: (510) 483-9620

                                       N/A
--------------------------------------------------------------------------------
          (Former name or former address, if changed since last report)

         Check the  appropriate  box below if the Form 8-K filing is intended to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (SEE General Instruction A.2. below):

|_|      Written  communications  pursuant to Rule 425 under the  Securities Act
         (17 CFR 230.425)

|_|      Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17
         CFR 240.14a-12)

|_|      Pre-commencement  communications  pursuant to Rule  14d-2(b)  under the
         Exchange Act (17 CFR 240.14d-2(b))

|_|      Pre-commencement  communications  pursuant to Rule 13e-4(c))  under the
         Exchange Act (17 CFR 240.13e-4c))





ITEM 7.01.  REGULATION FD DISCLOSURE.

On March 20, 2006,  Alpha  Innotech  Corp.  (the  "Company")  posted a letter to
stockholders from William F. Snider,  Chairman of the Company,  on the Company's
website. The text of the letter is attached hereto as Exhibit 99.1.


ITEM 9.01.  FINANCIAL STATEMENTS AND EXHIBITS.

         (c)      EXHIBITS

                  99.1     Letter  to  stockholders   from  William  F.  Snider,
                           Chairman of the Company


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                                    SIGNATURE

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                                ALPHA INNOTECH CORP.



Date:    March 20, 2006                By:      /S/ RONALD BISSINGER
                                          --------------------------------------
                                                Ronald Bissinger
                                                Chief Financial Officer


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                                  EXHIBIT INDEX

99.1           Letter to  stockholders  from William F. Snider,  Chairman of the
               Company


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