EXHIBIT 32.1



                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002




Pursuant to 18 U.S.C.  Section 1350,  as adopted  pursuant to Section 906 of the
Sarbanes-Oxley  Act of 2002, in connection  with the filing of the Annual Report
on Form 10-KSB/A for the Fiscal Year Ended  December 31, 2003 (the  "Report") by
Xtrana, Inc. ("Registrant"), the undersigned hereby certifies that:

1.       to the  best of my  knowledge,  the  Report  fully  complies  with  the
         requirements  of section 13(a) or 15(d) of the Securities  Exchange Act
         of 1934; and

2.       to the best of my knowledge,  the  information  contained in the Report
         fairly presents, in all material respects,  the financial condition and
         results of operations of Registrant.


Date:    April 28, 2004
                                        /S/ JAMES H. CHAMBERLAIN
                                        ------------------------------
                                        James H. Chamberlain
                                        Chief Executive Officer and
                                        Chief Financial Officer