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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 E4WJ+XX84uKrGSaw+iax4vhrVMVAbRSKCtpP9xjcb4Qs2w6JL/J70I/AtymrVyfz
 7hELy9/ULXIm5eXF8pQSfg==

<SEC-DOCUMENT>0001157523-05-011022.txt : 20051222
<SEC-HEADER>0001157523-05-011022.hdr.sgml : 20051222
<ACCEPTANCE-DATETIME>20051222155659
ACCESSION NUMBER:		0001157523-05-011022
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051220
FILED AS OF DATE:		20051222
DATE AS OF CHANGE:		20051222

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Snider William
		CENTRAL INDEX KEY:			0001340831

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14257
		FILM NUMBER:		051282257

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		510-483-9620

	MAIL ADDRESS:	
		STREET 1:		2401 MERCED STREET
		CITY:			SAN LEANDRO
		STATE:			CA
		ZIP:			94577

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALPHA INNOTECH CORP
		CENTRAL INDEX KEY:			0000830736
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				581729436
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2401 MERCED ST.
		CITY:			SAN LEANDRO
		STATE:			CA
		ZIP:			94577
		BUSINESS PHONE:		5104839620

	MAIL ADDRESS:	
		STREET 1:		2401 MERCED ST.
		CITY:			SAN LEANDRO
		STATE:			CA
		ZIP:			94577

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	XTRANA INC
		DATE OF NAME CHANGE:	20010702

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BIOPOOL INTERNATIONAL INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTRX BIOPOOL LTD
		DATE OF NAME CHANGE:	19890716
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>a5045569_ex.xml
<DESCRIPTION>ALPHA INNOTECH CORP. FORM 4-SNIDER
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-12-20</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000830736</issuerCik>
        <issuerName>ALPHA INNOTECH CORP</issuerName>
        <issuerTradingSymbol>APNO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001340831</rptOwnerCik>
            <rptOwnerName>Snider William</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ALPHA INNOTECH CORP.</rptOwnerStreet1>
            <rptOwnerStreet2>2401 MERCED STREET</rptOwnerStreet2>
            <rptOwnerCity>SAN LEANDRO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94577</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Common Stock (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.46</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-12-20</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>300000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-12-20</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>300000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>300000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The shares underlying this option shall vest and become exercisable with respect to 200,000 shares on June 30, 2006 and with
respect to 100,000 shares on December 31, 2006 subject to completion of certain milestones.</footnote>
        <footnote id="F2">Not applicable.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Haseeb Chaudhry, by power of attorney</signatureName>
        <signatureDate>2005-12-22</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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