Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2022

Accounting Policies [Abstract]

Schedule of Disaggregation of Revenue

In the following table, revenue is disaggregated by primary geographical market, major product line, and timing of revenue recognition.

In thousands of US dollars ($)	Year Ended December 31,
Primary geographical markets	2022		2021
North America		1,191		1,179
Europe		144		289
Asia		394		534
		1,729		2,002

In thousands of US dollars ($)	Year Ended December 31,
Major products/services lines	2022		2021
Hardware		761		1,104
Consumables		257		274
Contract research services		196		268
Agrochem Products		165		29
Sample preparation accessories		132		140
Technical support/extended service contracts		174		119
Shipping and handling		42		51
Other		2		17
		1,729		2,002

In thousands of US dollars ($)	Year Ended December 31,
Timing of revenue recognition	2022		2021
Transferred at a point in time		1,359		1,674
Transferred over time		370		328
		1,729		2,002

Schedule of Contract Balances

Contract balances

In thousands of US dollars ($)	December 31, 2022		December 31, 2021
Receivables, which are included in ‘Accounts Receivable’		295		155
Contract liabilities (deferred revenue)		60		41

Schedule of Future Related to Performance Obligations

The following table includes estimated revenue expected to be recognized in the future related to performance obligations that are unsatisfied (or partially unsatisfied) at the end of the reporting period.

In thousands of US dollars ($)	2023		2024		Total
Extended warranty service		58		2		60

Schedule of Inventories

Inventories are valued at the lower of cost (average cost) or net realizable value. The cost of Barocyclers consists of the cost charged by the contract manufacturer. The cost of manufactured goods includes material, freight-in, direct labor, and applicable overhead. The composition of inventory as of December 31, is as follows:

	2022			2021
Raw materials	$	188,587		$	296,892
Finished goods		1,480,769			1,193,158
Inventory reserve		(982,973	)		(342,496	)
Total	$	686,383		$	1,147,554

Schedule of Customer Concentration Risk Percentage

The following table illustrates the level of concentration of the below two groups within revenue as a percentage of total revenues during the years ended December 31:

	2022			2021
Top Five Customers		24	%		44	%
Federal Agencies		0	%		6	%

The following table illustrates the level of concentration of the below two groups within accounts receivable as a percentage of total accounts receivable balance as of December 31:

	2022			2021
Top Five Customers		93	%		82	%
Federal Agencies		0	%		5	%

Schedule of Computation of Loss Per Share

	2022			2021
Numerator:
Net loss attributable to common shareholders	$	(17,803,953	)	$	(22,685,459	)
Denominator for basic and diluted loss per share:
Weighted average common shares outstanding		11,058,356			6,636,523
Loss per common share - basic and diluted	$	(1.61	)	$	(3.42	)

Schedule of Anti-dilutive Securities Excluded from Computation of Earnings Per Share

The following table presents securities that could potentially dilute basic loss per share in the future. For all periods presented, the potentially dilutive securities were not included in the computation of diluted loss per share because these securities would have been anti-dilutive for the years ended December 31:

	2022		2021
Stock options		1,307,822		1,333,101
Convertible debt		6,915,754		5,232,118
Common stock warrants		16,278,769		16,207,108
Convertible preferred stock:
Series D Convertible Preferred		25,000		25,000
Series G Convertible Preferred		26,857		26,857
Series H Convertible Preferred		33,334		33,334
Series H2 Convertible Preferred		70,000		70,000
Series J Convertible Preferred		115,267		115,267
Series K Convertible Preferred		229,334		229,334
Series AA Convertible Preferred		8,645,000		8,649,000
		33,647,137		31,921,119

Summary of Assumptions for Grants of Stock Options

The following table summarizes the assumptions we utilized for grants of stock options to the three sub-groups of our stock option recipients during the year ended December 31, 2021 (there were no options granted in 2022):

Assumptions	CEO, other Officers and Employees
Expected life		6.0	(yrs)
Expected volatility		155.02	%
Risk-free interest rate		0.62	%
Forfeiture rate		5.00	%
Expected dividend yield		0.0	%

Schedule of Stock Based Compensation Expense

We recognized stock-based compensation expense of $215,098 and $254,615 for the years ended December 31, 2022 and 2021, respectively. The following table summarizes the effect of this stock-based compensation expense within each of the line items within our accompanying consolidated statements of operations for the years ended December 31:

	2022		2021
Research and development	$	79,891	$	128,094
Selling and marketing		24,687		22,233
General and administrative		110,520		104,288
Total stock-based compensation expense	$	215,098	$	254,615

Schedule of Assets and Liabilities Measured at Fair Value on Recurring Basis

The following tables set forth the Company’s financial assets that were accounted for at fair value on a recurring basis as of December 31, 2022:

			Fair value measurements at December 31, 2022 using:
	December 31, 2022		Quoted prices in active markets (Level 1)		Significant other observable inputs (Level 2)		Significant unobservable inputs (Level 3)
Equity Securities		63,638		63,638		-		-
Total Financial Assets	$	63,638	$	63,638	$	-	$	-

The following tables set forth the Company’s financial assets that were accounted for at fair value on a recurring basis as of December 31, 2021:

			Fair value measurements at December 31, 2021 using:
	December 31, 2021		Quoted prices in active markets (Level 1)		Significant other observable inputs (Level 2)		Significant unobservable inputs (Level 3)
Equity Securities	$	59,976	$	59,976		-		-
Total Financial Assets	$	59,976	$	59,976	$	-	$	-