Document and Entity Information	12 Months Ended
	Dec. 31, 2011
Document And Entity Information
Entity Registrant Name	PRESSURE BIOSCIENCES INC
Entity Central Index Key	0000830656
Document Type	S-1
Document Period End Date	Dec. 31, 2011
Amendment Flag	true
Current Fiscal Year End Date	--12-31
Is Entity a Well-known Seasoned Issuer?	No
Is Entity a Voluntary Filer?	No
Is Entity's Reporting Status Current?	No
Entity Filer Category	Smaller Reporting Company
Amendment Description	Amendment No. 1
Document Fiscal Period Focus	FY
Document Fiscal Year Focus	2011