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2. Summary of Significant Accounting Policies (Details 3)
 12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Summary Of Significant Accounting Policies Details 3    
Stock options 3,406,250pbio_StockOptions 1,771,708pbio_StockOptions
Convertible debt 5,453,571pbio_ConvertibleDebtDilutiveSecurities 2,242,024pbio_ConvertibleDebtDilutiveSecurities
Common stock warrants 19,182,201pbio_CommonStockWarrants 15,012,327pbio_CommonStockWarrants
Convertible preferred stock:    
Series D Convertible Preferred stock 750,000pbio_SeriesDConvertiblePreferred 750,000pbio_SeriesDConvertiblePreferred
Series G Convertible Preferred stock 865,700pbio_SeriesGConvertiblePreferred 1,453,200pbio_SeriesGConvertiblePreferred
Series H Convertible Preferred stock 1,000,000pbio_SeriesHConvertiblePreferred 1,000,000pbio_SeriesHConvertiblePreferred
Series H2 Convertible Preferred 2,100,000pbio_SeriesH2ConvertiblePreferred 0pbio_SeriesH2ConvertiblePreferred
Series J Convertible Preferred stock 3,546,000pbio_SeriesJConvertiblePreferred 5,087,500pbio_SeriesJConvertiblePreferred
Series K Convertible Preferred stock 11,416,000pbio_SeriesKConvertiblePreferred 4,000,000pbio_SeriesKConvertiblePreferred
Total potentially dilutive shares 47,719,722pbio_TotalPotentiallyDilutiveShares 31,316,759pbio_TotalPotentiallyDilutiveShares