We hereby consent to the incorporation by reference in the Registration Statements on Forms S-8 (File Nos. 333-30320, 333-24749 and 333-128594) of Pressure BioSciences, Inc. (formerly Boston Biomedica, Inc.) of our report dated March 23, 2006, except for Note 2 (iii), as to which the date is May 22, 2006, relating to the consolidated financial statements as of December 31, 2005 and for the years ended December 31, 2005 and 2004, which appears in this Annual Report on Form 10-KSB/A.