Notes Payable (Details) (USD $)	0 Months Ended	12 Months Ended				0 Months Ended		12 Months Ended			0 Months Ended	3 Months Ended
	Dec. 22, 2006	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010	Jan. 20, 2011	Mar. 03, 2010 Convertible Debt [Member]	Dec. 22, 2006 Convertible Debt [Member]	Dec. 31, 2012 Convertible Debt [Member] Days Y	Dec. 31, 2010 Convertible Debt [Member]	Jul. 02, 2010 Convertible Debt [Member]	Mar. 03, 2010 Convertible Debt [Member] Warrant [Member]	Jun. 30, 2010 Convertible Debt [Member] Fair value, inputs, level 2 [Member]	Mar. 31, 2010 Convertible Debt [Member] Fair value, inputs, level 2 [Member]
Debt Conversion [Line Items]
Proceeds from notes payable, In dollars							$ 40,000,000
Notes payable interest accrual rate							8.00%
Conversion of warrants to common stock, In shares							7,600,000
Debt instrument, convertible, conversion price, dollars per share							$ 5.25
Warrants received to purchase common stock, in shares							2,285,714
Investment warrants, exercise price, dollars per share							$ 5.50	$ 2.00
Business acquisition, purchase price allocation, assets acquired	33,000,000
Debt instrument, unamortized discount							6,272,566
Amortization of beneficial conversion features		0	0	(918,710)			8,482,090
Interest expense		0	12,111	4,837,688					783,346
Notes payable						40,000,000
Convertible notes payable						26,000,000
Warrants issued to extinguish debt, in shares						7,750,000					7,750,000
Common stock, exercise price, in dollars per share						$ 1.35					$ 1.35
Shares issued to extinguish debt, in shares											7,407,407
Derivative, loss on derivative												4,829,036	5,848,150
Days after anniversary warrants are exercisable								180
Warrants exercisable anniversary date (in years)								5
Days after study announcement								45
warrants and rights outstanding					16,193,037				13,471,832	5,509,893
Warrants and rights outstanding, adjustment									7,961,939
Reclassification of redeemable warrants to APICS		16,193,037
Change in amount of redeemable warrants reclassified to APICS				$ 2,721,205