Note 11 - Income Taxes (Details Textual) - USD ($) $ in Thousands	3 Months Ended	12 Months Ended
	Dec. 31, 2014	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent		35.00%	35.00%	35.00%
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount		$ 1,673	$ 3,134	$ (25,169)
Foreign Earnings Repatriated			9,850	5,442
Deferred Tax Liabilities, Undistributed Foreign Earnings		635	208
Unrecognized Tax Benefits that Would Impact Effective Tax Rate		1,778
Unrecognized Tax Benefits, Income Tax, Gross Penalties and Interest Disclosed	$ 489	455	475	489
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense		63	58	337
Amount of Tax and Intrest Paid as Final Settlement to the Tax Authority	1,487
Unrecognized Tax Benefits, Period Increase (Decrease)	$ 4,137
State and Local Jurisdiction [Member]
Operating Loss Carryforwards		98,200
Operating Loss Carryforwards, Valuation Allowance		$ 98,200
State and Local Jurisdiction [Member] | Earliest Tax Year [Member]
Open Tax Year		2012
Foreign Tax Authority [Member]
Operating Loss Carryforwards		$ 2,431
Operating Loss Carryforwards, Valuation Allowance		$ 2,431
Foreign Tax Authority [Member] | Earliest Tax Year [Member]
Open Tax Year		2010
Internal Revenue Service (IRS) [Member] | Domestic Tax Authority [Member] | Earliest Tax Year [Member]
Open Tax Year		2012
PharmaCore, Inc. [Member] | Internal Revenue Service (IRS) [Member]
Operating Loss Carryforwards		$ 11,300
Domestic Federal Valuation Allowance Release of Valuation Allowance Due to Profitability [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount				(26,902)
Domestic Valuation Allowance Change for Income Loss [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount				1,516
Foreign Valuation Allowance Change for Income Loss [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount		(621)	684	217
Domestic Valuation Allowance [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount		2,294	2,450	(25,386)
Domestic Valuation Allowance Changed Due to Domestic State Items [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount				1,516
Foreign Valuation Allowance [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount		(698)	(1,531)	1,923
Foreign Gains and Losses Related to Deferred Taxes and Currency Translation Adjustments Included in OCI [Member]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount		$ (77)	$ (2,215)	$ 1,706