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Note 7 - Goodwill and Intangible Assets (Details Textual) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Oct. 31, 2016
Amortization of Intangible Assets $ 1,011 $ 865 $ 530  
Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months 1,839      
Finite-Lived Intangible Assets, Amortization Expense, Year Two 1,894      
Finite-Lived Intangible Assets, Amortization Expense, Year Three 1,894      
Finite-Lived Intangible Assets, Amortization Expense, Year Four 1,883      
Finite-Lived Intangible Assets, Amortization Expense, Year Five 1,874      
Zenara [Member] | Restructuring Charges [Member]        
Impairment of Intangible Assets, Finite-lived   3,625    
Computer Software, Intangible Asset [Member]        
Capitalized Internal Software, Amount $ 2,297 $ 2,639    
PharmaCore, Inc. [Member]        
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Intangible Assets, Other than Goodwill       $ 6,900
PharmaCore, Inc. [Member] | Customer-Related Intangible Assets [Member]        
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Intangible Assets, Other than Goodwill       $ 6,900