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Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash flows from operating activities:    
Net loss $ (6,201) $ (6,883)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 836 884
Write-off of abandoned patents 374 50
Loss on sale of property and equipment 0 2
Compensation expense related to stock options and awards 804 1,534
Purchase of technology license with common stock 0 775
Changes in operating assets and liabilities:    
Receivables and other assets (1,902) (1,403)
Accounts payable and accrued expenses 65 (1,885)
Deferred revenue (138) 2,110
Deferred rent (416) (313)
Net cash used in operating activities (6,578) (5,129)
Cash flows from investing activities:    
Maturities of marketable securities 19,215 15,030
Purchases of marketable securities (25,143) (11,500)
Purchases of property and equipment (230) (58)
Patent expenditures 0 (53)
Net cash (used in) provided by investing activities (6,158) 3,419
Cash flows from financing activities:    
Net proceeds from issuance of common stock 7,759 3
Payment of withholding taxes for net settlement of restricted stock units (13) (23)
Net cash provided by (used in) financing activities 7,746 (20)
Net decrease in cash and cash equivalents (4,990) (1,730)
Cash and cash equivalents at beginning of period 13,450 20,471
Cash and cash equivalents at end of period $ 8,460 $ 18,741