5. Other Balance Sheet Accounts

Property and equipment consisted of the following at December 31 (in thousands):


	2013			2012
Equipment	$	18,027		$	19,660
Leasehold improvements		8,048			7,992

		26,075			27,652
Less accumulated depreciation and amortization		(22,140	)		(22,368	)

	$	3,935		$	5,284

Depreciation and amortization of equipment and leasehold improvements for each of the years ended December 31, 2013, 2012 and 2011, was $1.6 million.

Intangible assets consisted of the following at December 31 (in thousands):


	2013			2012
Licensed technology rights	$	—		$	4,015
Patent application costs		3,968			6,420

		3,968			10,435
Accumulated amortization licensed technology rights		—			(3,931	)
Accumulated amortization patent costs		(1,996	)		(3,691	)

	$	1,972		$	2,813

Amortization of licensed technology rights and patent application costs for the years ended December 31, 2013, 2012 and 2011, was $0.4 million, $0.4 million and $0.7 million, respectively. Estimated annual amortization for these assets for each of the years in the period from 2014 to 2018 is approximately $0.2 million.

Accounts payable and accrued expenses consisted of the following at December 31 (in thousands):


	2013		2012
Employee compensation	$	1,587	$	3,858
Clinical trial accruals		347		660
Accounts payable		395		377
Deferred rent		369		307
Post-termination benefit accrual		369		—
Other accrued liabilities		436		427

	$	3,503	$	5,629